Pathology Puzzles Project gives an opportunity to all the specialists to study interesting morphological cases. It is not only a good educational opportunity but also a chance to discuss the cases within the pathologists’ community. Every month three cases will be uploaded into the Digital Pathology system. Before uploading the cases minimum two specialists will validate them.

Case 31

2016-10-25_11-26-56The indurated area without clear boundaries, grayish-white colored, d= 1cm was found in the upper-outer quadrant of the left breast.    






Case 30

2016-10-25_11-22-59A woman, 1965 y. o. b.   

The tumor node in the lower-outer quadrant, with a fairly clear borders, 3,7×3,5×3 cm.

8 tissue lymph nodes were found: 0.5 – 15 cm in diameter  and also a conglomerate of two lymph nodes, 3,5x3x2 сm.    




Case 29

2016-10-25_11-05-54 A woman, 1951 y. o. b.

In 2012 – signet ring cell gastric cancer with metastases in the lymph nodes of the abdomen.

In 2014 – the serous solid- papillary adenocarcinoma of both ovaries structure with immunophenotype SK7 +, CA125 +, WT1 + (nuclear).

In 2015 – the metastasis of ovarian serous adenocarcinoma in hernial sac of anterior abdominal wall.

In 2016 –  tumor node in the central zone of the right breast, with fairly sharp edges, d=1mm.    


Case 28

Скриншот 2016-07-29 16.15.2655 year-old woman presented with clinically so-called “polyp” of uterine cervix.  More

Case 27

Скриншот 2016-07-29 16.13.35Man, 38 y. The lesion on the first toe of the left foot.  More

Case 25

case 25Patient, 26 years old. Tumor of the tongue was revealed and resected. Neoplasia in the lung has been revealed 3 months ago. More

Case 24

case 24Patient 23 years old complaints on bloody issues from vagina. Diagnostic curettage has been done. More

Case 23

case 23Patient 19 years old with retroperitoneal tumor. Incision biopsy has been done.


Case 22

case 22The 21-year-old patient was initially forwarded to a cardiology unit due to dyspnea, tachycardia, fatigue and night fever. These symptoms had been triggered by recent tonsillitis, so the patient was suspected to suffer from septic endocarditis and therefore received intensive antibacterial therapy. Further examination by spiral computed tomography revealed abdominal lymphadenopathy, while no abnormalities were detected by esophagogastroscopy and colonoscopy. Diagnostic laparoscopic biopsy of an affected lymph node was subsequently performed. More