This subcutaneous lymph node shows almost complete effacement by the proliferation of two morphologically distinct neoplastic elements; an epithelioid cell and spindle to ovoid cell.
The epithelioid cell is characterized by round to oval or indented nuclei with vesicular chromatin and variable prominent nuclei. The cytoplasm is lightly eosinophilic often with foamy or vacuolated appearance with indistinct cell borders.
This skin tumour infiltrate the dermis and efface the subcutaneous fatty tissue and is characterized by atypical cells with eosinophilic cytoplasm, round to oval often with horse-shoe nuclei and frequent multinucleated cells. The chromatin is vesicular and variable prominent nucleoli are seen. The tumour cell dissects the collagen bundles and moderate to abundant lymphoid infiltrate are seen on the background especially around the capillaries. Infrequent mitotic figures are present and proliferation index is around 15%. More
Both slides were reviewed and additionally reviewed in staff conference. Recut H&E stains x2 were prepared from both submitted blocks and immunostains for calponin and p63 were prepared from both blocks. Viewers concurred there are foci of DCIS Grade lll involving cores on both slides, with focal central comedo-type necrosis noted. No microinvasion is appreciated, confirmed by retained myoepilnelial cells highlighted by the p63 and calponin immunostains. More
The indurated area without clear boundaries, grayish-white colored, d= 1cm was found in the upper-outer quadrant of the left breast.
A woman, 1965 y. o. b.
The tumor node in the lower-outer quadrant, with a fairly clear borders, 3,7×3,5×3 cm.
8 tissue lymph nodes were found: 0.5 – 15 cm in diameter and also a conglomerate of two lymph nodes, 3,5x3x2 сm.
A woman, 1951 y. o. b.
In 2012 – signet ring cell gastric cancer with metastases in the lymph nodes of the abdomen.
In 2014 – the serous solid- papillary adenocarcinoma of both ovaries structure with immunophenotype SK7 +, CA125 +, WT1 + (nuclear).
In 2015 – the metastasis of ovarian serous adenocarcinoma in hernial sac of anterior abdominal wall.
In 2016 – tumor node in the central zone of the right breast, with fairly sharp edges, d=1mm.
55 year-old woman presented with clinically so-called “polyp” of uterine cervix. More
Man, 38 y. The lesion on the first toe of the left foot. More